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Solitary Testicular Myofibroma in a Rabbit
Tae-Un Kim1, Sang-Hwa Lee1, Yi-Rang Jung2
1College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
Journal of Comparative Pathology
|November 23, 2020
Summary
This study reports the first known case of a solitary testicular myofibroma in a rabbit. This rare mesenchymal tumor, originating from myofibroblasts, was identified in a six-year-old rabbit
Area of Science:
- Veterinary Pathology
- Comparative Oncology
- Mesencymal Tumors
Background:
- Myofibromas are mesenchymal tumors of myofibroblastic origin.
- They typically present as solitary or multicentric forms, predominantly affecting the head and neck in humans.
- Visceral myofibromas are rare in humans and have not been previously documented in animals.
Observation:
- A case of a six-year-old rabbit with an enlarged testis exhibiting a multinodular surface is presented.
- Surgical examination revealed a thick, white-yellow mass surrounding the testicular parenchyma.
- Histopathological analysis showed the mass composed of collagen and spindle cells.
Findings:
- Immunohistochemistry confirmed the spindle cells were positive for alpha-smooth muscle actin but negative for desmin, S-100, and von Willebrand factor.
- These findings differentiate the tumor from other spindle cell neoplasms.
- The tumor was diagnosed as a solitary testicular myofibroma.
Implications:
- This report represents the first documented instance of a solitary testicular myofibroma in any animal species.
- It expands the known anatomical distribution of myofibromas.
- This finding may contribute to a better understanding of mesenchymal tumors in veterinary medicine.
