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Related Experiment Video

Updated: Nov 29, 2025

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Autism Spectrum Disorder and Sleep.

Kyle P Johnson¹, Paria Zarrinnegar¹

¹Division of Child & Adolescent Psychiatry, Oregon Health & Science University, Mailcode: DC-7P, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.

Child and Adolescent Psychiatric Clinics of North America

|November 23, 2020

Summary

Children and adolescents with autism spectrum disorder (ASD) have high rates of sleep disturbances like insomnia. Effective treatments include behavioral interventions, parental education, and melatonin.

Keywords:

Autism Behavioral Children Insomnia Melatonin Pediatric Sleep

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A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

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Published on: October 11, 2018

Area of Science:

Pediatric Sleep Medicine
Neurodevelopmental Disorders

Background:

Sleep disturbances, especially insomnia, are prevalent in youth with autism spectrum disorder (ASD), exceeding general population rates.
Sleep deprivation in this population is linked to increased daytime behavioral issues and parental stress.

Purpose of the Study:

To review the epidemiology of sleep disturbances in children and adolescents with ASD.
To summarize the latest evidence-based treatment options for sleep problems in this demographic.

Main Methods:

Literature review of epidemiological studies on sleep disturbances in ASD.
Synthesis of current research on treatment efficacy for sleep issues in youth with ASD.

Main Results:

Autism spectrum disorder (ASD) is associated with significantly higher incidences of sleep disturbances, including insomnia.
Behavioral interventions, parental education, and melatonin demonstrate effectiveness in managing sleep problems.

Conclusions:

Sleep disturbances are a critical concern for children and adolescents with autism spectrum disorder (ASD).
A multi-faceted approach involving behavioral strategies, parent support, and pharmacological options like melatonin is recommended for treatment.