Cyclic stroke mortality variations follow sunspot patterns
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Updated: Nov 29, 2025
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Stella Geronikolou1, Alexandros Leontitsis2, Vasilis Petropoulos3
1Clinical, Translational and Experimental Surgery, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece.
Background:
Mapping time-structures is a burgeoning scientific field enriching the (P4) medicine models. Local evidence in Mediterranean populations is underinvestigated.
Methods:
The Censused stroke-related death events (D) in the largest East-Mediterranean port (Piraeus), during (1985-1989), when local population had diet (low fat/sugar, proteins and vegetables/fruits daily, and pure olive oil almost exclusively) and genetic homogeneity-later interrupted by the immigration into Greece in 1990; and Sunspot numbers were indexed by Wolf numbers (Rz) (1944-2004), and evaluated using Fast Fourier Analysis and Singular Spectrum Analysis in MATLAB.
Results:
D were turned with fluctuations >35% in Rz. A non-anthropogenic 6.8 days cycle was recognized.
Conclusions:
This study may be taken into consideration in future public health planning and chronotherapy evaluations.
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