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Hypocalcemia secondary to hypomagnesemia in a patient on liraglutide
J E L Habnouny1,2, I Jandou3, H Latrech1
1Department of Endocrinology, Diabetology, CHU Mohammed VI, Laboratory of Epidemiology and clinical research and public Health, Faculty of Medicine and Pharmacy, Mohamed Premier University, Oujda, Morocco.
Abstract:
A 73-year-old man with type 2 diabetes on Liraglutide with a history of coronary artery disease. Admitted to emergency for abdominal pain, severe diarrhea and episodes of tetany attacks. Laboratory workup reveals hypomagnesemia, hypocalcemia and normal parathormone (PTH). After intravenous administration of magnesium and calcium, the blood ionogram quickly normalized. In addition, plasma levels of intact parathyroid hormone increased immediately after magnesium administration. Strongly suggests that hypocalcemia resulted from a disruption of adequate parathyroid hormone secretion caused by hypomagnesemia which in turn was caused by severe diarrhea under treatment with Liraglutide.
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