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Updated: Nov 29, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Lung ultrasound in outpatient approach to children with suspected COVID 19
Giuseppe Gregori1, Roberto Sacchetti2
1Local Health Unit, Department of Primary Care, Medicina di Gruppo Pediatrica Piccolo Daino, Via Conciliazione 45/A, 29121, Piacenza, Italy. g.greg@agonet.it.
Insights
Lung ultrasound (LUS) effectively identified interstitial lung lesions in children with suspected COVID-19 infection (CV19), even without respiratory distress. This imaging technique aids in diagnosing CV19 in pediatric patients when other tests are limited.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Medical Imaging
Background:
- COVID-19 infection (CV19) in children typically presents with mild symptoms like fever and cough.
- Dyspnea and hypoxemia are rare, with limited data on lung involvement in pediatric CV19.
- Diagnostic challenges arose during the pandemic due to limited testing availability and reliability, complicating CV19 suspicion confirmation in children.
Purpose of the Study:
- To evaluate the efficacy of lung ultrasound (LUS) in detecting interstitial lung lesions in children with persistent cough and suspected CV19.
- To assess LUS as a tool for corroborating CV19 infection in pediatric cases.
Main Methods:
- Retrospective analysis of 32 children with persistent cough (≥3 days) and suspected CV19, seen between March 1st and April 30th, 2020.
- All children underwent clinical examination, oximetry measurement, and lung ultrasound (LUS).
Main Results:
- Twenty out of 32 children showed ultrasound lesions consistent with CV19.
- Many children with LUS findings did not exhibit clinical signs of respiratory distress.
- Lung ultrasound (LUS) demonstrated higher sensitivity than clinical examination in detecting lung injury in children with suspected CV19.
Conclusions:
- Lung ultrasound (LUS) is valuable for identifying undiagnosed interstitial lung lesions in children with suspected CV19, particularly when diagnostic tests are unavailable or overwhelmed.
- LUS can reinforce the diagnostic suspicion of CV19 in pediatric patients presenting with persistent cough.
- This imaging approach is highly beneficial in outpatient settings and resource-limited areas for managing suspected pediatric CV19 cases.
Background:
Children with COVID 19 infection (CV19) generally have a mild disease whose main symptoms are fever and cough. Dyspnoea and hypoxemia are rarely reported and few data are available on the frequency and extent of lung involvement in children with CV19. In addition, due to the limited availability of diagnostic tests in Italy during the pandemic period and the relative reliability of the test results, the diagnostic suspicion of CV19 infection in most of the children was difficult to confirm. The aim of this study is to evaluate if lung ultrasound (LUS) was able to highlight typical interstitial lung lesions in children with persistent cough and suspected CV19, providing corroborating evidence of CV19 infection.
Methods:
We retrospectively analysed the data of 32 children who came consecutively to our outpatient observation in the period between March 1st and April 30th, 2020 because of the presence of persistent cough for at least 3 days and with suspected CV19. All the children undergone clinical examination, oximetry measurement and LUS.
Results:
Twenty over thirty-two children had US lesions compatible with the presence of CV19, many of them without clinical signs of respiratory distress. LUS is much more sensitive than clinical examination to detect lung injury in children with suspected CV19.
Conclusion:
In the absence of reliable, highly sensitive diagnostic tests or when nasal swab is unworkable or there are too many requests to be performed quickly due to the pandemic, LUS should be used in children with persistent cough for whom a CV19 is suspected because it can highlight undiagnosed interstitial lung lesions and reinforce the diagnostic suspicion of CV19 This approach can be very useful in outpatient settings and in areas with limited medical resources such as developing countries.
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