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Updated: Nov 29, 2025

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Nonrandomized Clinical Trial of the Effectiveness of a Laxative Treatment Protocol to Time of First Bowel Movement
Suzanne Stiffler1, Andrea Staiti1, Patricia Tuck1
1Department of Interventional Services, Patient Care Services/Division of Nursing, Mercy Medical Center, Baltimore, MD.
Purpose:
The purpose of this pilot study was to determine the efficacy of a proactive laxative protocol for constipation prevention in patients undergoing uterine artery embolization (UAE).
Design:
A nonrandomized clinical trial.
Methods:
A nonrandomized trial study design was piloted using a convenience sample of 35 patients undergoing UAE in the course of 1 year.
Findings:
There was a statistically significant difference (P < .0001) in time of first bowel movement after UAE when patients followed a proactive laxative protocol. A combination of senna and stool softener taken twice a day for 2 days preoperatively was associated with a shorter time to first bowel movement postoperatively.
Conclusions:
This pilot study supports the benefits of a proactive laxative protocol in helping achieve procedural recovery uncomplicated by constipation in patients undergoing UAE.
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