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Updated: Nov 29, 2025

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Large bowel obstruction from advanced prostate cancer in a 41-year-old: the role of genetic testing
J B Jonosky1, N De Villiers2, R Wadee3
1Department of Urology, Helen Joseph Hospital, South Africa, Department of Paediatric Urology, Rahima Moosa Mother & Child (Coronation) Hospital, South Africa and Division of Urology, Department of Surgery, Faculty of Health Sciences, University of the Witwatersrand, South Africa.
Summary:
We report a rare presentation of an advanced prostate cancer (Gleason 10) in a 41-year-old man with complete large bowel obstruction relieved by loop colostomy. His young age prompted a search for a cause and genetic testing confirmed chromosome 10 PTEN deletion. His immediate family members were screened and counselled appropriately. This case outlines the role of genetic testing in young males with prostate cancer.

