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Related Experiment Videos

Roxithromycin in skin and soft tissue infections.

P Agache1, P Amblard, G Moulin

  • 1University Department of Dermatology, Hôpital St-Jacques, Besançon, France.

The Journal of Antimicrobial Chemotherapy
|November 1, 1987
PubMed
Summary
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Roxithromycin and doxycycline showed similar effectiveness in treating skin infections. Both antibiotics achieved 92% clinical and bacteriological success rates in this randomized trial.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pharmacology

Background:

  • Skin infections are common conditions requiring effective antibiotic treatment.
  • Assessing the comparative efficacy of different antibiotic agents is crucial for clinical practice.

Purpose of the Study:

  • To compare the clinical and bacteriological effectiveness of roxithromycin and doxycycline in patients with infected skin conditions.

Main Methods:

  • A double-blind, randomized investigation involving 76 patients.
  • Patients were treated with either roxithromycin (150 mg twice daily) or doxycycline (200 mg once daily).
  • Groups were well-matched for demographic and clinical characteristics.

Main Results:

  • Roxithromycin demonstrated a 92% clinical and 92% bacteriological effectiveness.

Related Experiment Videos

  • Doxycycline showed an 82% clinical and 82% bacteriological effectiveness.
  • The observed differences in effectiveness between the two antibiotics were not statistically significant.

    • Conclusions:

    • Roxithromycin and doxycycline exhibit comparable efficacy in treating infected skin conditions.
    • Both antibiotics represent viable therapeutic options for managing bacterial skin infections.