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Hepatoblastoma with multiple tumors in a school-aged child

Yugo Takaki1, Takahiro Yamashita2, Natsumi Kataoka1

  • 1Department of Pediatrics Japanese Red Cross Kumamoto Hospital Kumamoto Japan.

Clinical Case Reports
|November 25, 2020
PubMed

Abstract:

Clinicians need to consider hepatoblastoma in the differential even in school-aged children or adolescents presenting with multiple liver tumors.

Keywords:
hepatoblastomamultiple tumorsschool‐aged children

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The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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