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Updated: Nov 28, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Racemic Monomer-Based One-Handed Helical Polymer Recognizes Enantiomers through Auto-Evolution of Its Helical
Tomoyuki Ikai1, Tomoyuki Kurake1, Shogo Okuda1
1Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya, 464-8603, Japan.
Abstract:
A racemic monomer-based optically inactive polyacetylene folds into a one-handed helix assisted by a nonracemic alcohol, which can separate various enantiomers as a chiral stationary phase in chromatography. The chiral-resolving power is virtually identical to that of the enantiopure monomer-based one-handed helical polyacetylene. Because of its unique static memory of the induced helicity, the original racemic polyacetylene expresses an auto-evolution of its helical handedness over time, and at the same time, chirality of the nonracemic alcohol is discriminated accompanied by successive enhancement of its optical purity enantioselectively adsorbed on the helical polyacetylene owing to the chiral filter effect as directly monitored by NMR, which contributes to further enhancing the helix-sense-excess of the helical polyacetylene.
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