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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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A Nanobar-Supported Lipid Bilayer System for the Study of Membrane Curvature Sensing Proteins in vitro
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Chiral molecules on curved colloidal membranes.

Sk Ashif Akram1, Arabinda Behera, Prerna Sharma

  • 1Department Of Physics, Indian Institute Of Technology Bombay, Powai-400076, Mumbai, India. asain@phy.iitb.ac.in.

Soft Matter
|November 25, 2020
PubMed
Summary

Colloidal membranes with chiral rod molecules form complex tilt patterns on curved surfaces. A new covariant theory explains these patterns on minimal surfaces, predicting novel arrangements for future membrane design.

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Area of Science:

  • Materials Science
  • Soft Matter Physics
  • Surface Chemistry

Background:

  • Colloidal membranes, self-assembled monolayers of aligned rod-like molecules, serve as templates for creating membranes with specific shapes and curvature.
  • The molecular chirality of constituent rods often leads to tilting relative to the membrane normal.

Purpose of the Study:

  • To develop a covariant theory for predicting tilt patterns on curved colloidal membranes, specifically focusing on minimal surfaces.
  • To understand the interplay of forces governing tilt patterns, including depletion forces, nematic interactions, molecular chirality, and boundary effects.

Main Methods:

  • Development of a covariant theoretical framework to describe molecular tilt patterns.
  • Application of the theory to minimal surfaces such as helicoids and catenoids, which have recently been synthesized.
  • Analysis of the competition between various physical forces influencing tilt orientation.

Main Results:

  • Prediction of several non-uniform molecular tilt patterns on curved minimal surfaces.
  • The theoretical predictions offer explanations for some existing experimental observations.
  • The study identifies novel tilt patterns that await experimental verification.

Conclusions:

  • The covariant theory provides a robust framework for understanding molecular tilt in colloidal membranes on complex geometries.
  • The predicted tilt patterns offer insights into the self-assembly mechanisms and potential functionalities of chiral colloidal membranes.
  • This research paves the way for designing advanced membranes with tailored properties by controlling molecular tilt.