Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineered Red Blood Cell-Derived Extracellular Vesicles With Klotho Peptide Protect the Kidney From Fibrosis.

Journal of extracellular biology·2026
Same author

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Correction: Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis.

Molecular neurodegeneration·2026
Same author

Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.

Pharmacological research·2026
Same author

Bivalent ligands targeting oxytocin receptor homodimers selectively activate distinct G protein and β-arrestin pathways.

Biochemical pharmacology·2026
Same author

Biomimetic lipid nanoparticles for RNA delivery to breast cancer microenvironment cells by enhanced homotypic and heterotypic adhesion.

Journal of colloid and interface science·2026
Same journal

Tracking Synthetic Adhesins on Bacterial Surfaces with Immunofluorescence Microscopy.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Post-Selection Methods for Analyzing mRNA Display Selections and Optimization of Hits.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

High-Performance Computing in Tandem Mass Spectrometry (MS/MS) Peptide Identification.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Engineering and Adapting Disulfide-Containing Proteins to Enable Intracellular Functionality.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

AI-Driven Protein Research: From Prediction to Design.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Methods for the In Vitro Selection of Protein and Peptide Libraries Using mRNA Display.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Nov 28, 2025

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.5K

Self-Assembling Peptide Hydrogels for 3D Microarrays.

Greta Bergamaschi1, Alessandro Strada1, Roberto Frigerio1

  • 1National Research Council of Italy-Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR), Milan, Italy.

Methods in Molecular Biology (Clifton, N.J.)
|November 25, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a printable, self-assembling peptide hydrogel for advanced biosensing. This novel matrix enables efficient 3D microarray bioassays, demonstrating potential for rapid arbovirus infection diagnostics.

Keywords:
3D bioassaysMicroarraysSelf-assembly peptide hydrogelsSupramolecular nanostructures

More Related Videos

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.2K
Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications
09:19

Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications

Published on: September 15, 2017

7.5K

Related Experiment Videos

Last Updated: Nov 28, 2025

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.5K
Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.2K
Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications
09:19

Patterning Bioactive Proteins or Peptides on Hydrogel Using Photochemistry for Biological Applications

Published on: September 15, 2017

7.5K

Area of Science:

  • Biomaterials Science
  • Analytical Chemistry
  • Immunodiagnostics

Background:

  • Biosensing platforms are crucial for diagnostics and therapeutics.
  • Hydrogels offer excellent matrices for immobilizing biomolecules in biosensors.
  • Self-assembling peptide hydrogels present unique advantages for bioassay development.

Purpose of the Study:

  • To evaluate a self-assembling peptide hydrogel as a matrix for 3D microarray bioassays.
  • To demonstrate the hydrogel's suitability for diagnostic applications.
  • To showcase its use in detecting arbovirus infections.

Main Methods:

  • Development and characterization of a printable, self-assembling peptide hydrogel.
  • Integration of the hydrogel into a 3D microarray bioassay format.
  • Application of the bioassay for arbovirus infection detection via immunoassay.

Main Results:

  • The peptide hydrogel demonstrated printability and self-adhesive properties.
  • The hydrogel facilitated fast analyte diffusion, crucial for sensitive detection.
  • Successful application in a diagnostic immunoassay for arbovirus detection was achieved.

Conclusions:

  • Self-assembling peptide hydrogels are effective matrices for 3D microarray bioassays.
  • This hydrogel platform offers a promising approach for advanced diagnostic tools.
  • The developed system shows potential for rapid and efficient arbovirus diagnostics.