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Updated: Nov 28, 2025

In Vitro Imaging and Quantification of the Drug Targeting Efficiency of Fluorescently Labeled GnRH Analogues
Published on: March 21, 2017
GnRH in the Treatment of Hypogonadotropic Hypogonadism
Carlo Bettocchi1, Marco Rinaldi1, Francesco Sebastiani1
1Department of Emergency and Organ Transplantation - Urology, Andrology, and Kidney Transplantation Unit - University of Bari, Italy.
Abstract:
Gonadotropin-releasing hormone (GnRH) is the focus of the scientific debate for the treatment of hypogonadotropic hypogonadism. Sexual maturation and reproductive function depend on the pulsatile secretion of GnRH that are mainly congenital and may or may not be associated with other genetic anomalies or syndromes. Clinical manifestations include a wide range of metabolic, endocrine, and psychologic dysfunctions. The following manuscript focuses on the effects of GnRH therapy on fertility and cognitive abilities, aiming to investigate the current level of evidence for this treatment regimen. Current literature has been reviewed with the aim of highlighting the key findings on these two aspects.
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