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Updated: Nov 28, 2025

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Phenols, Flavors, and the Mediterranean Diet
Manel Issaoui1, Amélia Martins Delgado2, Giorgia Caruso3
1University of Monastir, Faculty of Medicine, Lab-NAFS Nutrition-Functional Food & Vascular Health, 5019 Monastir, Tunisia.
Phenolic compounds, found abundantly in spices and herbs, offer antioxidant benefits and influence food flavor and color. Understanding their sensory impact can encourage consumption of healthy, phytonutrient-rich foods.
Area of Science:
- Food Science
- Nutritional Science
- Phytochemistry
Background:
- Phenolics (phenols) are plant secondary metabolites with antioxidant properties.
- Dietary intake of phenolics varies globally, with coffee, tea, wine, fruits, and vegetables being common sources.
- Spices and culinary herbs are exceptionally rich in polyphenols, despite small consumption amounts.
Purpose of the Study:
- To summarize global dietary intake of polyphenols across various dietary patterns.
- To review the contribution of natural phenolic compounds to food and beverage flavor.
- To explore the role of phenolics in the Mediterranean Diet.
Main Methods:
- Literature review of dietary intake studies on polyphenols.
- Analysis of research on phenolic compounds' impact on food sensory properties (flavor, color, taste, astringency).
- Examination of phenolic content in foods relevant to the Mediterranean Diet.
Main Results:
- Spices and herbs are significant, often underestimated, sources of dietary polyphenols.
- Phenolic compounds contribute to bitter taste and astringency but also influence food color and aroma.
- Understanding sensory impacts can guide strategies to increase consumption of phenolic-rich foods.
Conclusions:
- Phenolic compounds play a dual role in diet: providing health benefits and influencing food sensory attributes.
- Dietary patterns, like the Mediterranean Diet, rich in diverse phenolic sources, are associated with health.
- Further research into sensory impacts can promote healthier eating habits and increase phytonutrient intake.
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