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Updated: Nov 28, 2025

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
Published on: May 2, 2018
Intestinal spirochetosis: normal intestinal flora or etiology of diarrhea?
María Del Mar Díaz Alcázar1, Alicia Martín-Lagos Maldonado2, Javier Luis López Hidalgo3
1UGC Aparato Digestivo, Hospital Universitario Clínico San Cecilio, España.
Abstract:
A 22-year-old male began with up to 12 loose stools per day, with mucus and no blood. They were present for two months, even during the night. Moreover, he complained of abdominal pain and weight loss. There were no findings on the blood tests. Fecal calprotectin was 225 μg/g. Stool microbiology tests were negative. Ileocolonoscopy displayed normal mucosa but the histological study of the biopsies showed Treponemas genus Brachispira. The patient had a sexual risk behavior. Treatment with metronidazole was initiated with clinical improvement.
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