Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Diagnosis and Staging of Patients with Prostate Cancer: Report from the 2025 Advanced Prostate Cancer Consensus Conference (APCCC) Diagnostics.

European urology·2026

Same author

Evaluation of audiovisual and auditory interventions on exam anxiety during whole-body magnetic resonance imaging in cancer patients: a quasi-experimental study.

Cancer imaging : the official publication of the International Cancer Imaging Society·2026

Same author

Diagnostic performance of CT-based node-RADS for detecting metastatic lymph nodes in melanoma and comparison with short-axis and roundness index.

Clinical imaging·2026

Same author

TNF inhibitors for the long-term management of juvenile idiopathic arthritis associated uveitis: real-life data from the ITHACA cohort.

Expert opinion on biological therapy·2026

Same author

Pancreatic cystic lesions: position paper of the SIRM-AISP multidisciplinary group.

La Radiologia medica·2026

Same author

Constraining the intensive absorption properties of ambient organic aerosol particles based on pan-European observations.

NPJ climate and atmospheric science·2026

Search research articles

Related Experiment Video

Updated: Nov 28, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

In-bore MRI targeted biopsy.

Martina Gurgitano¹, Eleonora Ancona², Duilia Maresca³

¹Division of Radiology, IEO European institute of oncology IRCCS, Milan, Italy . martina.gurgitano@gmail.com.

Acta Bio-Medica : Atenei Parmensis

|November 27, 2020

Summary

Multiparametric MRI (mpMRI) with targeted biopsy (MRI-TBx) improves prostate cancer diagnosis over standard biopsy. This MRI-guided approach reduces unnecessary biopsies and overdiagnosis of insignificant cancers while maintaining detection of significant prostate cancer.

More Related Videos

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Related Experiment Videos

Last Updated: Nov 28, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Area of Science:

Urology
Medical Imaging
Oncology

Background:

Prostate cancer (PCa) diagnosis traditionally relies on PSA levels, DRE, and imaging, with biopsy being mandatory.
Standard Biopsy (SBx) involves random prostate sampling, risking missed tumors (up to 30%) and inaccurate risk stratification.

Purpose of the Study:

To evaluate the efficacy of the 'MRI pathway' (mpMRI and MRI-TBx) compared to the 'standard pathway' (SBx) for diagnosing prostate cancer.

Main Methods:

Utilized multiparametric Magnetic Resonance Imaging (mpMRI) for detecting suspicious lesions.
Employed MRI-guided Target Biopsy (MRI-TBx) for direct sampling of suspicious areas.
Compared outcomes with traditional Standard Biopsy (SBx) in patients with elevated PSA and/or abnormal DRE.

Main Results:

The 'MRI pathway' demonstrated superiority over the 'standard pathway' in multiple trials.
MRI-TBx significantly reduced the total number of biopsies performed.
It decreased the diagnosis of clinically insignificant PCa, thereby reducing overdiagnosis, while maintaining or improving the detection of clinically significant PCa (cs-PCa).

Conclusions:

The 'MRI pathway' represents a significant advancement in prostate cancer diagnostics.
mpMRI combined with MRI-TBx offers a more accurate and efficient diagnostic strategy, minimizing unnecessary procedures and overdiagnosis.
This approach enhances the diagnosis of clinically significant prostate cancer.