Related Experiment Video
Updated: Nov 28, 2025

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
19.2K
Extended endonasal approaches for pituitary adenomas
Domenico Solari1, Elena D'Avella1, Ilaria Bove1
1Division of Neurosurgery, Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.
Journal of Neurosurgical Sciences
|November 27, 2020
Summary
Large pituitary adenomas invading surrounding areas pose treatment challenges. The extended endoscopic endonasal approach offers a safe alternative for maximum tumor resection while preserving function.
Area of Science:
- Neurosurgery
- Endocrinology
- Skull Base Surgery
Background:
- Pituitary adenomas with extensive invasion present significant surgical challenges.
- Tumor invasiveness can limit complete resection and increase complication risks.
- Traditional approaches may be insufficient for large or invasive pituitary adenomas.
Purpose of the Study:
- To evaluate the extended endoscopic endonasal approach for complex pituitary adenomas.
- To discuss the indications, advantages, limitations, and potential pitfalls of this technique.
Main Methods:
- Review of the extended endoscopic endonasal approach for pituitary adenoma treatment.
- Analysis of surgical outcomes, including resection extent and functional preservation.
Main Results:
- The extended endoscopic endonasal approach provides a wide, close-up view for safe tumor exposure.
- This technique allows for maximal safe resection and preservation of neurological and endocrine functions.
- It serves as a viable alternative to transcranial routes for specific pituitary adenomas.
Conclusions:
- The extended endoscopic endonasal approach is a valuable technique for managing complex pituitary adenomas.
- Careful patient selection and surgical expertise are crucial for optimal outcomes.
- This approach expands the possibilities for treating challenging pituitary tumors endoscopically.

