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Updated: Nov 28, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Interventions to Increase Multivitamin Use Among Women in the Interconception Period: An IMPLICIT Network Study
Mario P DeMarco1, Maha Shafqat2, Michael A Horst2
1Department of Family Medicine and Community Health, University of Pennsylvania, 51 N. 39th Street, Philadelphia, PA, 19104, USA. mario.demarco@pennmedicine.upenn.edu.
Maternal counseling during pediatric visits can increase multivitamin (MVI) use. Directly providing MVI samples significantly boosted MVI adherence compared to advice alone, improving prenatal health.
Area of Science:
- Maternal and Child Health
- Public Health Interventions
- Preventive Medicine
Background:
- Congenital anomalies affect 3% of US infants annually, with neural tube defects being a significant concern.
- Multivitamins (MVIs) with folic acid are proven to reduce birth defects, yet many women have suboptimal intake.
- The interconception period presents a critical window for improving maternal health behaviors.
Purpose of the Study:
- To evaluate the effectiveness of the IMPLICIT ICC model in promoting MVI use among mothers.
- To identify interventions that increase MVI adherence in women of reproductive age.
- To leverage well child visits (WCVs) for maternal health risk screening and intervention.
Main Methods:
- The IMPLICIT ICC model was used to screen mothers attending WCVs for children aged 0-24 months.
- Mothers were assessed for behavioral risks, including MVI and family planning use.
- A mixed-effects logistic regression analyzed the odds of behavior change in MVI use post-intervention.
Main Results:
- 37.7% of mothers reported not using MVIs during WCVs.
- Interventions were provided to 64.0% of mothers to improve MVI use.
- Receiving MVI samples (OR 3.09) or provider advice (OR 1.64) increased MVI use at subsequent visits.
Conclusions:
- Pediatric WCVs offer a valuable opportunity for maternal counseling and behavioral change.
- Direct provision of MVIs is more effective than provider advice in increasing reported MVI use.
- Targeted interventions during WCVs can improve MVI adherence in at-risk women.
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