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Related Concept Videos

Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

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Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
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Fatigue01:21

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Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
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Heart Failure VII: Nursing Interventions01:30

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The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
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Cardiomyopathy VI: Nursing Management01:29

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Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
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Increased pulse rate01:17

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Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
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Heart Failure VI: Adjunct Therapies01:22

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Related Experiment Video

Updated: Nov 28, 2025

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Approach to Fatigue: Best Practice.

Jason C Dukes1, Matthew Chakan2, Aaron Mills3

  • 1Internal Medicine Department, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 565, Norfolk, VA 23507, USA.

The Medical Clinics of North America
|November 28, 2020
PubMed
Summary

Diagnosing fatigue requires a careful history and physical exam, not extensive tests. Primary fatigue, or system exertion intolerance disease, is managed with exercise and cognitive behavioral therapy, as no FDA-approved drugs exist.

Keywords:
Chronic fatigue syndromeFatigueMyalgic encephalitisSleepinessSystemic exertion intolerance diseaseTiredness

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Area of Science:

  • Internal Medicine
  • Clinical Diagnostics

Background:

  • Fatigue presents with broad differential diagnoses, necessitating a rational diagnostic approach.
  • Fatigue can stem from underlying medical conditions or exist as a primary disorder.

Purpose of the Study:

  • To emphasize the importance of clinical evaluation in diagnosing fatigue.
  • To outline management strategies for primary and secondary fatigue.

Main Methods:

  • Review of diagnostic approaches for fatigue.
  • Discussion of management principles for fatigue based on its etiology.

Main Results:

  • A thorough history and physical examination are crucial for diagnosing fatigue.
  • Diagnostic tests are often unhelpful for fatigue diagnosis.
  • Secondary fatigue management relies on treating the underlying condition.
  • Primary fatigue, or system exertion intolerance disease, lacks FDA-approved medications.

Conclusions:

  • Effective fatigue diagnosis hinges on clinical assessment rather than extensive testing.
  • Treatment for primary fatigue focuses on individualized exercise and cognitive behavioral therapy.