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Updated: Nov 28, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
Quantitative interactions between Candida albicans and the mutans streptococci in patients with Down Syndrome
A-G Linossier1, B Martinez, C-Y Valenzuela
1Gran Avenida 6477, Depto. 208 Santiago, Chile alinossi@gmail.com.
Background:
Oral microorganisms produce damage through the transfer to bloodstream, colonizing other tissues or direct damage in the oral cavity. Aim to study the quantitative interactions between C. albicans and the mutans streptococci and ms serotypes in the saliva of the oral cavity of patients with Down syndrome (DS).
Material And Methods:
Included 120 patients of both genders, 60 patients with Down syndrome (DS) and 60 pa- tients as a control group (CG). Samples of saliva were taken, and bacteria and fungi were grown on TYCSB and Saboureaud agar. Microbiological, serological and quantitative analyses were performed to determine the kind of isolated of microorganisms corresponding to the ms c, e, f and k for species S. mutans and d and g for S. sobrinus and C. albicans. Electronic scanning microscopy was employed to visualize and confirm the colonies under study. Statistics analysis included t-test proofs for matched data test, Scheffé and ANOVA.
Results:
Forming units (CFU) per mL of saliva of C. albicans a significant difference was observed among DS
Conclusions:
These results show a significant non-random association between these two commensal microorganisms in different patient groups.

