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Comparison of Methods for Measuring Cyclodeviation.

Laura Liebermann1, Sarah R Hatt1, David A Leske1

  • 1Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.

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Summary
This summary is machine-generated.

The double-Maddox rod test shows good agreement with the largest single-Maddox rod values and synoptophore cross-in-circle targets for measuring cyclodeviation. Other methods demonstrated poorer agreement, indicating a need for further research.

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Area of Science:

  • Ophthalmology
  • Vision Science

Background:

  • Cyclodeviation, a rotational eye misalignment, can impact visual function.
  • Accurate measurement of cyclodeviation is crucial for diagnosis and management.
  • Various clinical tests exist, but their comparative accuracy is not fully established.

Purpose of the Study:

  • To compare the diagnostic accuracy of the double-Maddox rod test against other common methods for measuring cyclodeviation.

Main Methods:

  • A retrospective cohort study analyzed data from 153 adult patients with cyclodeviation.
  • Measurements were obtained using the double-Maddox rod test, fusible and nonfusible synoptophore targets, single-Maddox rod, and fundus photography.
  • Statistical analyses included mean differences, 95% confidence intervals, intraclass correlation coefficients, and Bland-Altman plots.

Main Results:

  • Good agreement was found between the double-Maddox rod test and the largest single-Maddox rod values (ICC=0.82) and synoptophore cross-in-circle targets (ICC=0.79).
  • Poorer agreement was observed with synoptophore house targets (ICC=0.71) and fundus photography (ICC=-0.02 to 0.21).
  • Differences increased with greater cyclodeviation for single-Maddox rod and fundus photography, with significant correlations noted.

Conclusions:

  • The double-Maddox rod test demonstrates good agreement with specific single-Maddox rod and synoptophore measurements for cyclodeviation.
  • Less agreement was found with other tested methods, particularly fundus photography.
  • Further research is warranted to determine which cyclodeviation measurement best correlates with clinical symptoms.