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Published on: November 5, 2021
Advanced drug delivery systems can assist in targeting coronavirus disease (COVID-19): A hypothesis
Meenu Mehta1, Parteek Prasher2, Mousmee Sharma3
1Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411, Punjab, India.
Abstract:
The highly contagious coronavirus, which had already affected more than 2 million people in 210 countries, triggered a colossal economic crisis consequently resulting from measures adopted by various goverments to limit transmission. This has placed the lives of many people infected worldwide at great risk. Currently there are no established or validated treatments for COVID-19, that is approved worldwide. Nanocarriers may offer a wide range of applications that could be developed into risk-free approaches for successful therapeutic strategies that may lead to immunisation against the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) which is the primary causative organism that had led to the current COVID-19 pandemic. We address existing as well as emerging therapeutic and prophylactic approaches that may enable us to effectively combat this pandemic, and also may help to identify the key areas where nano-scientists can step in.
Insights
Nanocarriers show promise for developing safe and effective treatments and immunizations against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing the COVID-19 pandemic. This research explores therapeutic and prophylactic strategies utilizing nanocarriers to combat the global health crisis.
Area of Science:
- Nanotechnology
- Virology
- Pharmacology
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, has led to a global health crisis with over 2 million cases in 210 countries.
- The pandemic has resulted in a severe economic crisis due to containment measures.
- Currently, no universally approved treatments exist for COVID-19.
Purpose of the Study:
- To explore the potential of nanocarriers in developing therapeutic and prophylactic strategies against SARS-CoV-2.
- To identify key areas for nano-scientists to contribute to combating the COVID-19 pandemic.
- To review existing and emerging approaches for treating and preventing COVID-19.
Main Methods:
- Review of existing and emerging therapeutic and prophylactic approaches.
- Focus on the application of nanocarriers for drug delivery and immunization.
- Identification of research gaps and opportunities in nanomedicine for infectious diseases.
Main Results:
- Nanocarriers offer a versatile platform for developing risk-free therapeutic strategies.
- Potential for nanocarriers in creating effective immunizations against SARS-CoV-2.
- Nanotechnology can play a crucial role in combating the COVID-19 pandemic.
Conclusions:
- Nanocarriers represent a promising avenue for novel COVID-19 treatments and vaccines.
- Further research in nanomedicine is essential for pandemic preparedness and response.
- Collaboration between nano-scientists and medical researchers can accelerate the development of effective interventions.
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