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Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
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Data-science ready, multisite, human diffusion MRI white-matter-tract statistics.

Garikoitz Lerma-Usabiaga1,2,3, Pratik Mukherjee4,5, Michael L Perry6

  • 1Department of Psychology, Stanford University, 450 Jane Stanford Way, Jordan Hall Building, 94305, Stanford, California, USA. garikoitz@gmail.com.

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|December 1, 2020
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Summary
This summary is machine-generated.

We provide a data-science-ready dataset of human white matter tracts from diffusion MRI scans. This resource simplifies complex neuroimaging analysis for broader scientific collaboration and discovery.

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Area of Science:

  • Neuroscience
  • Medical Imaging
  • Data Science

Background:

  • White matter tracts are crucial for human brain function and behavior.
  • Diffusion MRI data analysis requires specialized computational neuroimaging and neuroanatomy expertise.
  • Accessibility of diffusion MRI data is limited for non-experts.

Purpose of the Study:

  • To create a curated, data-science-ready dataset of human white matter tract diffusion MRI measurements.
  • To facilitate analysis by non-diffusion MRI experts, accelerating research.
  • To share multisite data capturing inter-center variation.

Main Methods:

  • Acquisition of diffusion MRI data from three different MRI centers.
  • Processing raw data into a standardized, data-science-ready format.
  • Utilizing a computational system for reproducibility and provenance tracking.

Main Results:

  • A curated dataset of white matter tract diffusion MRI measurements is now available.
  • The dataset includes measures of within- and between-MRI center variation.
  • A reproducible computational framework ensures data integrity from scanner to analysis.

Conclusions:

  • The shared dataset lowers the barrier for data scientists to study white matter tracts.
  • This initiative promotes broader engagement and faster advancements in human white matter research.
  • Standardized, accessible data is key to unlocking new insights in neuroscience.