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Updated: Nov 28, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
The association between statewide vaping prevalence and COVID-19
Dongmei Li1, Daniel P Croft2, Deborah J Ossip3
1Department of Clinical & Translational Research, University of Rochester Medical Center, Rochester, NY, USA.
Electronic cigarette users (vapers) may be more susceptible to COVID-19. Higher state-level vaping prevalence correlated with increased COVID-19 cases and deaths, suggesting a need for further research into vaper vulnerability.
Area of Science:
- Public Health
- Epidemiology
- Respiratory Medicine
Background:
- Electronic cigarette use (vaping) is linked to impaired immune responses.
- Previous research suggests potential increased vulnerability to respiratory infections among vapers.
- The specific susceptibility of vapers to COVID-19 remains largely unexamined.
Purpose of the Study:
- To investigate the association between statewide e-cigarette use prevalence and COVID-19 incidence and mortality.
- To determine if vapers exhibit increased susceptibility to coronavirus disease 2019 (COVID-19).
Main Methods:
- Utilized integrated state-level data from BRFSS, US Census Bureau, and 1.3 Acres for 2018.
- Employed generalized estimating equation (GEE) models with negative binomial distribution and log link functions.
- Examined associations between vaping prevalence and COVID-19 cases/deaths from January 21, 2020, to April 25, 2020, adjusting for smoking prevalence.
Main Results:
- Statewide vaping prevalence ranged from 2.86% to 6.42%.
- A statistically significant positive association was found between vaping prevalence and both COVID-19 cases and deaths.
- A 1% increase in vaping prevalence correlated with a 0.3139 increase in COVID-19 cases and a 0.3730 increase in COVID-19 deaths (log scale).
Conclusions:
- Ecological study findings suggest increased COVID-19 susceptibility among vapers on a state level.
- The observed positive associations warrant further investigation into the relationship between vaping and COVID-19 outcomes.
- Public health strategies may need to consider the risks associated with e-cigarette use in the context of pandemics.
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