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Updated: Nov 27, 2025

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
Published on: June 21, 2011
An open, modular, and flexible micro X-ray computed tomography system for research.
1University of Stuttgart, Institute of Applied Mechanics (CE), Pfaffenwaldring 7, D-70569 Stuttgart, Germany.
Researchers developed a flexible, modular micro X-ray Computed Tomography (μXRCT) system for material microstructural characterization. This open-design system aids researchers in building their own experimental setups or deciding between custom and commercial scanners.
Area of Science:
- Materials Science
- Engineering
- Physics
Background:
- Microstructural characterization is crucial for understanding material properties.
- Existing X-ray Computed Tomography (XRCT) systems can be expensive and inflexible.
- There is a need for adaptable, open-source XRCT solutions for research.
Purpose of the Study:
- To present a modular and open micro X-ray Computed Tomography (μXRCT) system.
- To provide guidance for researchers setting up their own experimental XRCT systems.
- To demonstrate the flexibility and capabilities of a custom-built μXRCT system.
Main Methods:
- Detailed description of the modular hardware components of the μXRCT system.
- Implementation of a modular software concept for system control and data processing.
- Development of a method for bad detector pixel compensation to improve projection data quality.
- Performance evaluation focusing on achievable spatial resolution.
Main Results:
- The presented μXRCT system exhibits high flexibility due to its modular and open design.
- A reliable method for bad pixel correction was successfully implemented, enhancing data quality.
- Spatial resolution performance was thoroughly investigated and documented.
- Demonstration of the system's versatility through three distinct application case studies.
Conclusions:
- The modular and open μXRCT system offers a flexible and cost-effective alternative to commercial scanners.
- The system facilitates advanced experimental setups and in situ studies for microstructural analysis.
- The presented design and methods empower researchers to build and optimize their own XRCT facilities.
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