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Updated: Aug 13, 2026
09:37
Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[Hemodynamic changes caused by laparotomy during aorto-iliac surgery]
S Winnock1, G Janvier, M Césarini
1Département d'Anesthésie-Réanimation I, Hôpital Pellegrin-Tripode, Bordeaux.
Annales Francaises D'Anesthesie Et De Reanimation
|January 1, 1987
Summary
Abdominal aortic surgery causes significant hemodynamic shifts, including increased cardiac output and heart rate, alongside decreased vascular resistance and mean arterial pressure. These changes may involve nervous system stimulation and vasoactive substance release.
Area of Science:
- Cardiovascular Physiology
- Surgical Anesthesia
Context:
- Abdominal aortic surgery involves extensive manipulation.
- General anesthesia and controlled ventilation are standard.
- Hemodynamic monitoring is crucial during such procedures.
Purpose:
- To assess hemodynamic changes during abdominal aortic surgery before aortic clamping.
- To investigate the physiological responses to abdominal manipulation.
Summary:
- A study monitored 53 patients undergoing elective abdominal aortic surgery.
- Key parameters included mean arterial pressure, cardiac index, heart rate, and vascular resistances.
- Opening the peritoneal cavity and mesenteric traction led to increased cardiac index (+40.7%), heart rate (+28.61%), and cutaneous circulation (+50%), with decreased systemic vascular resistance (-39.16%) and mean arterial pressure (-15.7%).
Impact:
- Findings reveal significant hemodynamic alterations during abdominal aortic surgery.
- Observed cardiovascular collapse and erythema suggest complex physiological responses.
- The study suggests potential vagal and sympathetic nervous system stimulation and vasoactive substance release, requiring further investigation.
