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Challenges in coronary heart disease prevention - experiences from a long-term follow-up study in Norway
Insights
Lifestyle behaviors and lipid management in chronic coronary heart disease (CHD) patients remained suboptimal over 4.7 years. Increased physical inactivity and persistent risk factors highlight the need for intensified secondary prevention strategies.
Area of Science:
- Cardiology and Cardiovascular Health
- Public Health and Epidemiology
- Behavioral Medicine
Background:
- Chronic coronary heart disease (CHD) management requires ongoing lifestyle and lipid control for secondary prevention.
- Longitudinal data on risk factor management in post-CHD populations are crucial for evaluating healthcare effectiveness.
Purpose of the Study:
- To assess longitudinal changes in lifestyle behaviors and lipid management among patients with established coronary heart disease (CHD).
- To identify trends in modifiable risk factors and medication adherence over a 4.7-year follow-up period.
Main Methods:
- A multi-center cohort study involving 1127 CHD patients, with follow-up data collected from 707 participants.
- Data collection included hospital records, questionnaires, and clinical examinations, with analysis using univariate statistics.
- Baseline data were collected 16 months post-CHD event, with follow-up conducted in 2019.
Main Results:
- Over 4.7 years, smoking, obesity, anxiety, and depression rates remained largely unchanged, but low physical activity increased from 53% to 58%.
- Statin use remained high (92-94%), with increased use of high-intensity statins (49% to 54%) and ezetimibe (5% to 15%).
- Only 73% reported primary care consultations for CHD in the past year; non-attendees had higher smoking rates.
Conclusions:
- Coronary heart disease outpatients exhibit persistent suboptimal risk factor control during long-term follow-up.
- Intensified risk management, including lifestyle and psychological support, is essential for improving secondary prevention and patient outcomes.
- Enhanced primary care follow-up may be necessary to address persistent risk factors like smoking.
Abstract:
Objective. To determine longitudinal changes in lifestyle behaviour and lipid management in a chronic coronary heart disease (CHD) population. Design. A multi-centre cohort study consecutively included 1127 patients at baseline in 2014-2015, on average 16 months after a CHD event. Data were collected from hospital records, a questionnaire and clinical examination. Seven hundred and seven of 1021 eligible patients participated in a questionnaire-based follow-up in 2019. Data were analysed with univariate statistics. Results. After a mean follow-up of 4.7 years (SD 0.4) from baseline, the percentage of current smokers (15% versus 16%), obesity (23% versus 25%) and clinically significant symptoms of anxiety (21% versus 17%) and depression (13% versus 14%) remained unchanged, whereas the proportion with low physical activity increased from 53% to 58% (p < .001). The proportions with reduced physical activity level were similar in patients over and under 70 years of age. Most patients were still taking statins (94% versus 92%) and more patients used high-intensity statin (49% versus 54%, p < .001) and ezetimibe (5% versus 15%, p < .001) at follow-up. 73% reported ≥1 primary-care consultation(s) for CHD during the last year while 27% reported no such follow-up. There were more smokers among participants not attending primary-care consultations compared to those attending (19% versus 14%, p = .026). No differences were found for other risk factors. Conclusions. We found persistent suboptimal risk factor control in coronary outpatients during long-term follow-up. Closer follow-up and intensified risk management including lifestyle and psychological health are needed to improved secondary prevention and outcome of CHD. Trial registration: Registered at ClinicalTrials.gov: NCT02309255.Registered at 5 December 2014, registered retrospectively.
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