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Amlodipine Induced Massive Ascites, a Rare Clinical Case
Sema Nur Arasan1, Ezgi Coskun Yenigun, Simal Koksal Cevher
1University of Health Science, Ankara City Hospital, Department of Internal Medicine, Ankara, Turkey. sema.n.arasan@gmail.com.
Iranian Journal of Kidney Diseases
|December 5, 2020
Summary
This case report highlights amlodipine-induced massive serous ascites in a renal transplant patient. It emphasizes considering drug side effects, like calcium channel blockers, for unexplained ascites.
Area of Science:
- Nephrology
- Pharmacology
- Gastroenterology
Background:
- Calcium channel blockers (CCBs) are widely used for hypertension.
- Peripheral edema is a common CCB side effect.
- Dihydropyridine CCBs have been linked to chylous ascites in peritoneal dialysis patients.
Observation:
- A rare case of amlodipine-induced massive serous ascites in a 30-year-old male renal transplant recipient is presented.
Findings:
- This case is the first reported instance of amlodipine-associated serous ascites in the literature.
- The patient developed massive ascites, a rare adverse effect of amlodipine.
Implications:
- Highlights the importance of considering iatrogenic causes, specifically amlodipine, in patients presenting with unexplained ascites.
- Suggests that amlodipine, a commonly prescribed CCB, may be associated with serous ascites, a previously unreported side effect.
- Underscores the need for vigilance in identifying drug-induced conditions, even with well-established medications.
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