In situ self-assembled cationic lanthanide metal organic framework membrane sensor for effective MnO₄^- and ascorbic...

Developing portable membrane sensors to accurately detect the biomolecule ascorbic acid (AA) is extremely important for food safety and human health. Herein, we successfully design and synthesize a novel cationic metal organic framework (Eu-pbmc, Hpbmc = 2-(pyridine-2-yl)-1H-benzimidazole-5-carboxylic acid) and assemble polyacrylonitrile/Eu-pbmc membrane (PEM) by an in-situ growth strategy. Benefiting from the appreciable loading of Eu-pbmc nanoparticles and high water permeation flux, PEM possesses effective detection for MnO₄^- with a limit of detection (LOD) of 17 nM. Utilizing the cationic porous framework, we load MnO₄^- into PEM and construct a "on-off-on" system for effective AA detection. The oxidative MnO₄^- can be reduced by AA and the resulting turn-on luminescence can reflect the concentration of AA. Compared with pure Eu-pbmc crystals, PEM exhibits improved AA detection performance with LOD of 48 nM and detection time of 1 min via a concise detection operation. The stable membrane sensor realizes an accurate detection in real biological samples, meeting the practical requirement. Moreover, an IMP logic gate is helpful to analyze MnO₄^- and AA in water. The proposed novel luminescence platform as well as reasonable "on-off-on" luminescence mode provide a promising method for AA detection.