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Do Older Adults with Overactive Bladder Demonstrate Impaired Executive Function Compared to Their Peers Without OAB?
William Gibson1, Asad Makhani1, Kathleen F Hunter2
1Division of Geriatric Medicine, University of Alberta, Edmonton, AB.
Canadian Geriatrics Journal : CGJ
|December 7, 2020
Summary
Older adults with overactive bladder (OAB) show slower executive function, specifically on the Trail Making Test B (TMT-B). This suggests a link between OAB and cognitive changes in the aging brain.
Area of Science:
- Gerontology
- Neuroscience
- Urology
Background:
- Urinary continence relies on continuous sensory processing and suppression of voiding urges.
- Urinary incontinence (UI) and lower urinary tract symptoms (LUTS) are common, increasing with age.
- Central nervous system changes, not just urinary tract issues, may contribute to age-related LUTS.
Purpose of the Study:
- To investigate potential executive function impairments in older adults diagnosed with overactive bladder (OAB).
Main Methods:
- A cross-sectional study compared cognitive performance in adults aged 65+ with and without OAB.
- Participants completed the Trail Making Test B (TMT-B) and simple reaction time (SRT) tests.
- OAB criteria included urgency, weekly urgency incontinence, and high daytime frequency; controls had low B-SAQ scores.
Main Results:
- 35 of 56 participants had OAB.
- The OAB group demonstrated significantly longer completion times for the TMT-B compared to controls (103s vs. 77s, p=0.003).
- No significant difference in simple reaction time (SRT) was observed between groups.
Conclusions:
- Overactive bladder in older adults is associated with measurable deficits in executive function, specifically demonstrated by slower TMT-B performance.
- This finding suggests a correlation between OAB and impaired executive function in the elderly population.
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