Effects of onion extract containing concentrated cysteine sulfoxides on sleep quality: a randomized, double-blind,

Yuya Nakayama1, Miki Makita2, Satomi Nozaki1

  • 1Research Center for Basic Science, Research and Development, Quality Assurance Division, Nisshin Seifun Group Inc., Saitama, 356-8511 Japan.

Insights

Onion extract rich in cysteine sulfoxides improved sleep quality in healthy adults. This natural compound reduced stress and enhanced sleep transitions, promoting better rest.

Area of Science:

  • Nutritional Science
  • Sleep Medicine
  • Biochemistry

Background:

  • Sleep disturbances affect overall health and well-being.
  • Cysteine sulfoxides are sulfur-containing compounds found in onions.
  • Stress is a known contributor to poor sleep quality.

Purpose of the Study:

  • To investigate the impact of onion extract with concentrated cysteine sulfoxides on sleep quality.
  • To assess the effects of onion extract on sleep parameters and stress indicators.

Main Methods:

  • A randomized, double-blind, placebo-controlled, crossover study design.
  • Inclusion of 30 healthy adults experiencing sleep dissatisfaction.
  • Administration of onion extract tablets or placebo for 5 days.

Main Results:

  • Significant increases in delta power during non-rapid eye movement sleep and the first sleep cycle.
  • Observed significant reduction in sleep latency.
  • Demonstrated a significant decrease in salivary alpha-amylase levels, indicating reduced stress.

Conclusions:

  • Onion extract containing concentrated cysteine sulfoxides effectively improves sleep quality.
  • The extract demonstrates stress-alleviating properties, contributing to better sleep.
  • It promotes a smoother transition into sleep, beneficial for individuals with sleep issues.

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