Non-enzymatic glucose sensor based on a g-C₃N₄/NiO/CuO nanocomposite

Area of Science:

• Materials Science
• Electrochemistry
• Nanotechnology

Background:

• Diabetes mellitus is a global health concern requiring accurate glucose monitoring.
• Existing glucose sensors often face limitations such as enzyme instability and high cost.
• Development of non-enzymatic glucose sensors offers a promising alternative for reliable detection.

Purpose of the Study:

• To develop and characterize a novel non-enzymatic glucose sensor.
• To investigate the electrocatalytic properties of a g-C3N4/NiO/CuO nanocomposite for glucose detection.
• To evaluate the sensor's performance for potential blood glucose monitoring applications.

Main Methods:

• Synthesis and characterization of g-C3N4/NiO/CuO nanocomposite using FE-SEM, TEM, EDX, XRD, and BET.
• Electrochemical characterization using cyclic voltammetry.
• Amperometric detection of glucose at a modified glassy carbon electrode (GCE).

Main Results:

• The g-C3N4/NiO/CuO/GCE demonstrated superior electrocatalytic activity compared to modified electrodes lacking one or more components.
• The sensor exhibited a wide linear range (0.4 μM to 8.5 mM) with a low detection limit (0.1 μM).
• High sensitivity (362.12 μA mM⁻¹ cm⁻²), excellent reproducibility, selectivity, and long-term stability were achieved.

Conclusions:

• The developed non-enzymatic glucose sensor based on g-C3N4/NiO/CuO/GCE shows excellent performance.
• The sensor is a promising candidate for accurate and reliable blood glucose sensing.
• This work contributes to the advancement of electrochemical sensors for diabetes management.