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Emergence of ancient convalescent plasma (CP) therapy: To manage COVID-19 pandemic
Barsha Dassarma1, Satyajit Tripathy1, Motlalepula Matsabisa1
1Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Insights
Convalescent plasma (CP) therapy offers a potential immediate solution for controlling the COVID-19 pandemic. This review explores CP therapy
Area of Science:
- Immunology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, presents significant global health challenges.
- Limited preventive and therapeutic options exist due to the novel nature of the virus.
- Convalescent plasma (CP) therapy, an established immunotherapeutic technique, is being investigated as a potential intervention.
Purpose of the Study:
- To review the concept and understanding of convalescent plasma therapy.
- To assess the potential of CP therapy in controlling the SARS-CoV-2 pandemic.
- To provide support for the possible application of CP therapy in managing COVID-19.
Main Methods:
- Literature review of existing studies on convalescent plasma therapy.
- Analysis of the efficacy and application of CP in the context of COVID-19.
- Synthesis of current understanding regarding CP therapy's role in pandemic control.
Main Results:
- Convalescent plasma therapy has shown affirmative results against COVID-19.
- CP therapy may serve as an immediate and accessible option for managing the pandemic.
- The review supports the potential application of CP therapy.
Conclusions:
- Convalescent plasma therapy is a viable immunotherapeutic option for managing COVID-19.
- Further research and application of CP therapy are warranted to combat the SARS-CoV-2 pandemic.
- CP therapy could be an immediate savior against the virus.
Abstract:
Since December 2019, the human populations of the 195 global countries continue experiencing grave health and life threats due to the current COVID-19 pandemic. As a result of the novelty of the pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at present there is lack of preventive as well as therapeutic options for treating and managing the infection. The use of ancient immunotherapeutic technique - the convalescent plasma (CP) therapy, may act as an immediate and available option to control the COVID-19 pandemic. This review provides a concept and understanding on the CP therapy, its potential to control SARS-CoV-2 pandemic. The CP therapy might act as an immediate saviour for society from the virus. Although the CP therapy has exert affirmative result against COVID-19 it has not been recommended for long time use in COVID-19 and this review gives support for its possible application.
