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Acupuncture for opioid-induced constipation: Protocol for a systematic review and meta-analysis
Pu Yang1, Yuanchun Wang2, Yingchun Xiao1
1School of Acupuncture-Moxibustion and Tuina, Shaanxi University of Chinese Medicine, Xian.
Medicine
|December 8, 2020
Summary
This systematic review and meta-analysis protocol will assess acupuncture
Area of Science:
- Integrative oncology
- Gastroenterology
- Pain management
Background:
- Opioid-induced constipation (OIC) is a frequent complication in cancer patients receiving analgesics.
- Acupuncture is a recognized therapy for constipation, but its effectiveness for OIC requires systematic evaluation.
- This study addresses the need for evidence on acupuncture's role in managing OIC.
Purpose of the Study:
- To systematically evaluate the efficacy and safety of acupuncture for treating opioid-induced constipation (OIC).
- To provide a comprehensive assessment of existing clinical evidence through meta-analysis.
Main Methods:
- A systematic search of 7 electronic databases (4 Chinese, 3 English) for Randomized Controlled Trials (RCTs) up to September 31, 2020.
- Utilizing RevMan 5.3 and Stata 14.0 for meta-analysis.
- Employing EndNote X9.2 and the Cochrane Risk of Bias Tool for literature screening and quality assessment.
Main Results:
- The study will synthesize high-quality clinical evidence to determine the efficacy of acupuncture for OIC.
- Safety data regarding acupuncture treatment for OIC will also be presented.
Conclusions:
- The findings will offer evidence-based insights into the benefits of acupuncture for patients suffering from opioid-induced constipation.
- This systematic review and meta-analysis aims to inform clinical practice regarding acupuncture as a treatment for OIC.
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