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Topical corticosteroid induced ulcerated striae.

Shyam B Verma1, Bhushan Madke2

  • 1Nirvan Skin Clinic, Makarpura, Vadodara, India.

Anais Brasileiros De Dermatologia
|December 8, 2020
PubMed
Summary
This summary is machine-generated.

Misusing combination creams with clobetasol propionate can cause ulcerated striae. This highlights potential risks associated with potent topical corticosteroids and antimicrobial agents.

Keywords:
Adverse effectsStriae distensaeTopical steroidUlceration

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Topical corticosteroids are widely used for inflammatory skin conditions.
  • Fixed-dose combination creams offer convenience but require careful application.

Observation:

  • Four cases of ulcerated striae were observed.
  • These occurred after the misuse of combination creams containing clobetasol propionate, an antifungal, and an antibacterial agent.

Findings:

  • Misuse of potent topical corticosteroids combined with antimicrobials can lead to adverse cutaneous events.
  • Ulcerated striae represent a significant side effect of inappropriate application.

Implications:

  • Clinicians should educate patients on the correct use of combination dermatological preparations.
  • Awareness of these risks is crucial for preventing iatrogenic skin damage.