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Chemical sensing with Au and Ag nanoparticles
Verónica Montes-García1, Marco A Squillaci, Marta Diez-Castellnou
1University of Strasbourg, CNRS, ISIS UMR 7006, 8 Allée Gaspard Monge, F-67000 Strasbourg, France. samori@unistra.fr.
Chemical Society Reviews
|December 8, 2020
Summary
Noble metal nanoparticles offer high sensitivity and selectivity for fabricating advanced chemical sensors. These nanoparticle-based devices are crucial for effective environmental and health monitoring applications.
Area of Science:
- Nanotechnology
- Materials Science
- Analytical Chemistry
Background:
- Noble metal nanoparticles (NPs) possess a high surface-to-volume ratio and unique optical/electrical properties, making them excellent for sensing.
- Their sensitivity to environmental changes is critical for developing high-performance detection devices.
- NPs can be functionalized with molecular receptors for specific analyte detection.
Purpose of the Study:
- To review recent strategies for fabricating chemical sensors using noble metal NPs.
- To highlight sensors with optical or electrical readouts that offer high sensitivity and selectivity.
- To focus on applications in environmental and health monitoring.
Main Methods:
- Decoration of noble metal NPs with molecular building blocks for analyte recognition.
- Utilizing supramolecular recognition events for enhanced sensor selectivity.
- Development of sensing devices with optical or electrical readout mechanisms.
Main Results:
- Fabrication of highly sensitive and selective chemical sensors based on noble metal NPs.
- Demonstration of NP-based sensors for detecting specific analytes and complex mixtures.
- Achieving fast response times and full reversibility in sensor operation.
Conclusions:
- Noble metal NPs are versatile scaffolds for advanced chemical sensing technologies.
- These NP-based sensors show great promise for efficient environmental and health monitoring.
- The integration of nanotechnology with molecular recognition enables next-generation sensing devices.

