Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Future thinking and psychopathology: A review of dysfunction, intervention, and a roadmap for future research.

Behaviour research and therapy·2026
Same author

An Examination of Intolerance of Uncertainty in Schizophrenia.

Clinical psychology & psychotherapy·2025
Same author

Transdiagnostic and transtherapeutic strategies for optimising autobiographical memory.

Behaviour research and therapy·2024
Same author

Recalling and anticipating positive events to improve the positive affect and mental health of adolescents: A cluster randomized controlled trial in secondary schools.

Behaviour research and therapy·2024
Same author

Imagery rescripting and extinction: Effects on US expectancy, US revaluation, and the generalization of fear reduction.

Behaviour research and therapy·2024
Same author

Disclosure of suicidal ideation and behaviours: A systematic review and meta-analysis of prevalence.

Clinical psychology review·2023
Same journal

The impact of the Memory Support Intervention on therapist memory for treatment contents.

Behaviour research and therapy·2026
Same journal

Dismantling the mechanism of VR self-compassion training: A two-session controlled trial with active controls.

Behaviour research and therapy·2026
Same journal

Supporting children on therapy waitlists: A randomized controlled trial of a web-based parent-focused single session intervention for child anxiety.

Behaviour research and therapy·2026
Same journal

Examining the roles of biased expectancies and weighting of valenced information in trait anxiety-linked state affect when approaching potentially stressful future events.

Behaviour research and therapy·2026
Same journal

Problem-solving therapy versus supportive psychotherapy for Veterans with moderate suicide risk and chronic pain: A pilot randomized clinical trial.

Behaviour research and therapy·2026
Same journal

A meta-analysis of cognitive behavioral therapy for substance use disorder: Treatment effects by comparator type and consumption and psychosocial outcomes.

Behaviour research and therapy·2026
See all related articles

Related Experiment Video

Updated: Nov 26, 2025

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.9K

Computerized Memory Specificity Training (c-MeST) for major depression: A randomised controlled trial.

D J Hallford1, D W Austin1, K Takano2

  • 1School of Psychology, 1 Gheringhap Street, Deakin University, Geelong, Victoria, 3220, Melbourne, Australia.

Behaviour Research and Therapy
|December 8, 2020
PubMed
Summary
This summary is machine-generated.

Computerized Memory Specificity Training (c-MeST) improved memory recall and reduced depressive symptoms in adults with Major Depressive Episodes (MDE). This digital intervention shows promise for enhancing recovery rates and targeting cognitive vulnerabilities in MDE.

Keywords:
Autobiographical memory specificityDepressionMajor depressive episodeMemory specificityOvergeneral memoryRandomised controlled trial

More Related Videos

Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol
10:36

Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol

Published on: November 21, 2025

17
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.3K

Related Experiment Videos

Last Updated: Nov 26, 2025

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.9K
Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol
10:36

Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol

Published on: November 21, 2025

17
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.3K

Area of Science:

  • Psychiatry and Psychology
  • Cognitive Behavioral Therapy
  • Digital Therapeutics

Background:

  • Major Depressive Episodes (MDE) often show modest treatment response and high relapse rates, highlighting the need for novel interventions.
  • Cognitive vulnerabilities, such as deficits in autobiographical memory specificity, are implicated in MDE.
  • Memory Specificity Training (MeST) is a cognitive intervention designed to improve detailed memory recall.

Purpose of the Study:

  • To evaluate the efficacy of an online, computerized version of Memory Specificity Training (c-MeST) for adults experiencing a current Major Depressive Episode.
  • To assess the impact of c-MeST on memory specificity and depressive symptom severity.
  • To explore whether improvements in memory specificity mediate the effects of c-MeST on depressive symptoms.

Main Methods:

  • A randomized controlled trial was conducted with 245 adults (88.4% female, mean age 46.4) diagnosed with MDE.
  • Participants were randomized to either the c-MeST program or a wait-list control group.
  • Assessments of MDE criteria, memory specificity, and depressive symptoms were conducted at baseline and at one- and three-month follow-ups.

Main Results:

  • Fewer participants in the c-MeST group met MDE criteria at one-month follow-up compared to the control group (35.7% vs. 60.6%).
  • The c-MeST group demonstrated significantly higher memory specificity at all follow-up time-points (d=0.53-0.93) and lower depressive symptoms at one (d=0.57) and three months (d=0.67).
  • Changes in memory specificity significantly mediated the relationship between c-MeST and reduced depressive symptoms.

Conclusions:

  • Computerized Memory Specificity Training (c-MeST) is effective in enhancing memory specificity and reducing depressive symptoms in individuals with MDE.
  • c-MeST may accelerate recovery from Major Depressive Episodes by targeting cognitive deficits.
  • Further research is warranted to elucidate the precise mechanisms underlying c-MeST's therapeutic effects.