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MOG antibody-related disease with recurrent optic neuritis and sensory polyradiculoneuropathy: A case report
Tomoaki Shima1, Akira Tsujino1
1Department of Neurology and Strokology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Abstract:
Myelin oligodendrocyte glycoprotein (MOG) antibody-related diseases are inflammatory demyelinating conditions of the central nervous system (CNS) that induce a broad spectrum of symptoms. Since MOG is expressed exclusively in the CNS, the lesions are thought to be confined to the CNS. However, few cases of MOG antibody-related disease involve the peripheral nervous system (PNS); the mechanisms underlying such PNS involvement remain unclear. We herein present the case of a patient with MOG antibody-related disease with recurrent optic neuritis and sensory polyradiculoneuropathy unaccompanied by CNS lesions. Our report presents a novel phenotype of PNS involvement in MOG antibody-related disease.
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