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[Level and trend of low birth weight mortality in children under 1 year old in China, 2004-2018]
1Department of Information Management, National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China.
Insights
The low birth weight mortality rate in children under 1 year old in China decreased significantly from 2004 to 2018. However, the proportion of these deaths is rising, particularly affecting boys and those in central and western regions.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Low birth weight (LBW) is a critical determinant of infant mortality.
- Understanding temporal trends and demographic disparities in LBW mortality is essential for targeted interventions.
Purpose of the Study:
- To analyze the trends in low birth weight (LBW) mortality rates among children under one year old in China between 2004 and 2018.
- To examine disparities in LBW mortality across sex, urban/rural settings, and geographical regions.
Main Methods:
- Utilized the National Mortality Surveillance Data Set (2004-2018).
- Employed Joinpoint regression analysis to assess mortality rates, constituent ratios, and trends.
- Calculated Average Annual Percentage Change (AAPC) and 95% confidence intervals (CI) for trend analysis.
Main Results:
- The overall LBW mortality rate in children under one year declined with an AAPC of -8.0% (95% CI: -10.6% to -5.4%).
- The constituent ratio of LBW mortality showed an increasing trend (AAPC = 1.6%, 95% CI: 0.1% to 3.2%).
- Disparities in mortality rates between sexes, urban/rural areas, and regions diminished over time, though boys and urban populations initially had higher rates. The western region showed a faster increase in the constituent ratio of LBW mortality.
Conclusions:
- Despite a decreasing trend in the overall LBW mortality rate, its proportional contribution to infant deaths is increasing.
- Boys and children in central and western China represent key populations requiring focused maternal and child health interventions.
- Addressing regional and sex-based disparities remains crucial for comprehensive LBW mortality reduction strategies.
Abstract:
Objective: To analyze the level and trend of low birth weight mortality in children under 1 year old in China from 2004 to 2018. Methods: The published Data Set of National Mortality Surveillance from 2004 to 2018 was used to analyze the low birth weight mortality rate, constituent ratio and changing trend in boys and girls, in urban area and rural area and in different regions in China. The Joinpoint regression model fitted by the weighted least square method was used to analyze the time variation trend and calculate the annual percentage change (APC), the average annual percentage change (AAPC) and their 95% confidence intervals in each time period. Results: From 2004 to 2018, the low birth weight mortality rate in children under 1 year old in China showed a decreasing trend with an AAPC of -8.0% (95%CI: -10.6% --5.4%). The differences between boys and girls, between urban area and rural area and among different regions gradually reduced. From 2004 to 2018, the constituent ratio of low birth weight mortality showed an increasing trend with an AAPC of 1.6% (95%CI: 0.1%-3.2%). The mortality rate in urban area (38.74 per 100 000) was higher than that in rural area (30.44 per 100 000). The annual average declining speed of low birth weight mortality rate in urban area (AAPC=-3.4%, 95%CI: -7.0%-0.3%) was slower than that in rural area (AAPC=-9.3%, 95%CI: -12.0% --6.6%). The low birth weight mortality rate of boys (36.25 per 100 000) was higher than that of girls (28.22 per 100 000). The low birth weight mortality constituent ratio in western region showed an increasing trend, its average annual percentage change (AAPC=3.2%, 95%CI: 1.7%-4.8%) increased faster than that of the eastern region (AAPC=-0.5%, 95%CI: -2.3%-1.4%). In urban and rural areas and different regions, the rate of low birth weight mortality in boys was higher than that in girls. Conclusions: From 2004 to 2018, the mortality rate of low birth weight in children under 1 year old showed a downward trend, and the constituent ratio showed an upward trend. Boys and children living in central and western regions should be the key population for maternal and child health care.
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