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Rashes following cesarean delivery: a case report.
Jiwei Huang1, Ximei Zhu2, Caiyun Jiang2
1Department of Pharmacy, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. 947543512@qq.com.
Annals of Palliative Medicine
|December 11, 2020
Summary
A cesarean delivery patient developed rashes and itching from cefuroxime sodium and morphine. Stopping these drugs and providing supportive care resolved the adverse drug reactions.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
- Dermatology
Background:
- Perioperative medication use, including antibiotics and analgesics, is standard during cesarean delivery.
- Cefuroxime sodium, a cephalosporin antibiotic, is used for infection prophylaxis.
- Morphine hydrochloride, an opioid, is commonly administered for postoperative pain management.
Observation:
- A 29-year-old woman presented with widespread rashes and pruritus post-cesarean delivery.
- The adverse symptoms appeared after the administration of cefuroxime sodium and morphine hydrochloride.
- The patient's physical signs correlated temporally with the drug administration timeline.
Findings:
- The observed rashes and pruritus were identified as potential adverse drug reactions.
- Both cefuroxime sodium (cephalosporin) and morphine hydrochloride (opioid) are known to cause such dermatological side effects.
- Discontinuation of the suspect medications and symptomatic treatment led to symptom resolution.
Implications:
- Healthcare providers should be vigilant for potential adverse reactions to cefuroxime sodium and morphine.
- Close patient monitoring for dermatological side effects is crucial during the perioperative period.
- Prompt cessation of offending medications is recommended upon identification of adverse drug reactions.
