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Decolonization of Staphylococcus aureus

Sima L Sharara1, Lisa L Maragakis1, Sara E Cosgrove1

  • 1Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.

Infectious Disease Clinics of North America
|December 11, 2020
PubMed

Insights

Staphylococcus aureus decolonization strategies can reduce infection risks in various patient groups. This review synthesizes current literature to guide clinical practice for preventing S aureus-related complications.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Staphylococcus aureus (S aureus) infections lead to significant morbidity, mortality, and healthcare costs.
  • S aureus colonization increases the risk of both invasive and noninvasive infections.
  • Decolonization is explored as a method to reduce S aureus transmission and infection.

Purpose of the Study:

  • To review recent literature on S aureus decolonization.
  • To inform clinical practice regarding S aureus decolonization in diverse patient populations.

Main Methods:

  • Literature review of studies on S aureus decolonization.
  • Analysis of decolonization efficacy across different patient settings.

Main Results:

  • Evidence suggests decolonization is a viable strategy in specific patient groups.
  • Effectiveness varies based on patient population and intervention.

Conclusions:

  • S aureus decolonization is a promising approach to mitigate infection risks.
  • Further research and tailored strategies are needed for optimal implementation across various clinical settings.
Keywords:
Chlorhexidine bathingDecolonizationNasal mupirocinStaphylococcus aureus colonization

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