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Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data
Alexandr Shevtsov1, Gilles Vergnaud2, Asylulan Amirgazin3
1National Center for Biotechnology, Nur-Sultan, Kazakhstan ncbshevtsov@gmail.com.
Abstract:
We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected.
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