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Updated: Nov 26, 2025

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
Retroperitoneal castleman disease mimicking lymph node spread from clear renal cell carcinoma. A case report
Eurico Cleto Ribeiro de Campos1, Marcos Gonçalves Adriano Júnior1, Marcus Rivabem Winheski2
1Department of Oncology of Prevent Senior, São Paulo Group, São Paulo, Brazil.
Abstract:
Renal Cell Carcinoma (RCC) corresponds to 3% of the neoplasms in the adults. Surgery is the main mode of treatment, which can be associated toretroperitoneal lymphadenectomy in the presence of clinically tumor positive lymph nodes. Castleman Disease (CD) is a rare lymphoproliferative disorder, with little-known etiopathogenesis. It rarely affects the retroperitoneum. Thorax, neck, and abdomen are more frequently affected. Therefore, CD can simulate lymphatic spread from RCC to the retroperitoneum, also leading to a possible misdiagnosis, or diagnosis concerning a paraneoplastic syndrome due to RCC.

