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Updated: Nov 26, 2025

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18F-FDG PET/CT imaging in a patient with solitary primary sacral lymphoma
Guan Nan Li1, Liu Xiao, Lin Li
1Department of Nuclear Medicine, West China Hospital; Sichuan University, No.37, Guoxue Alley, Chengdu, Sichuan (610041), People's Republic of China. lilinnuclear@163.com.
Abstract:
Solitary primary bone lymphoma of the sacrum is rare. We report a case of a 77-year-old male patient who presented with unexplained numbness and pain in the right lower extremity for over 2 months. Tumor markers and other laboratory were unremarkable. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed a solitary osteolytic bone lesion of the sacrum with intense 18F-FDG uptake (SUVmax=10.7). The subsequent biopsy confirmed the diagnosis of diffuse large B-cell lymphoma. After one cycle of R-CHOP, the neurological symptoms of the patient improved significantly.
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