SEPIA-Susceptibility mapping pipeline tool for phase images

Area of Science:

• Medical Imaging
• Computational Physics
• Neuroimaging

Background:

• Quantitative susceptibility mapping (QSM) is a sensitive MRI technique for quantifying iron deposition.
• QSM distinguishes paramagnetic and diamagnetic materials like hemorrhage and calcification.
• Increasing interest exists for QSM in both research and clinical settings.

Purpose of the Study:

• To present an open-source processing pipeline tool for QSM.
• To simplify the QSM workflow for researchers with varying experience levels.
• To create a flexible platform for integrating and sharing QSM methods.

Main Methods:

• Developed SuscEptibility mapping PIpeline tool for phAse images (SEPIA).
• Integrated various open-source QSM toolboxes into a unified framework.
• Implemented an interactive graphical user interface for pipeline construction and execution.

Main Results:

• SEPIA offers a flexible and user-friendly approach to QSM processing.
• The tool simplifies the complex QSM pipeline optimization.
• Facilitates the integration of new QSM algorithms and methods.

Conclusions:

• SEPIA enhances the accessibility and efficiency of QSM research.
• The open-source platform promotes collaboration and the adoption of state-of-the-art QSM techniques.
• SEPIA is a valuable tool for both novice and experienced QSM researchers and developers.