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Prevalence of Comorbid Asthma and Related Outcomes in COVID-19: A Systematic Review and Meta-Analysis

Shuang Liu1, Yang Cao1, Tian Du2

  • 1Department of Allergy & Clinical Immunology, National Clinical Research Center for Immunologic Diseases, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China; School of Clinical Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

The Journal of Allergy and Clinical Immunology. in Practice
|December 14, 2020
PubMed

Insights

Asthma prevalence in COVID-19 patients varies globally. Individuals with asthma show no increased COVID-19 severity but have a reduced risk of death, indicating a potentially protective effect.

Area of Science:

  • Pulmonary Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • The relationship between asthma and COVID-19 outcomes is not well-understood.
  • Investigating asthma's impact on COVID-19 is crucial for patient management.

Purpose of the Study:

  • To determine asthma prevalence in COVID-19 patients.
  • To compare COVID-19 outcomes between patients with and without asthma.

Main Methods:

  • Systematic review and meta-analysis of 131 studies.
  • Inclusion of 410,382 patients with COVID-19.
  • Random-effects model used for pooled estimates.

Main Results:

  • Global asthma prevalence in COVID-19 patients ranged from 1.1% to 16.9%.
  • No significant differences in hospitalization, severity, or ventilation were observed.
  • Patients with asthma had a lower risk of death (RR, 0.65).

Conclusions:

  • Asthma prevalence in COVID-19 patients varies significantly by region.
  • Asthma is not linked to increased COVID-19 severity or poorer prognosis.
  • Asthma may be associated with a reduced risk of mortality in COVID-19 patients.
Abstract

Keywords:
AsthmaCOVID-19PrevalencePrognosisSeverity

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