Related Experiment Video
Updated: Nov 26, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data
Nina J Karlin1,2, Matthew R Buras3, Heidi E Kosiorek3
1Division of Hematology & Medical Oncology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA.
Aim:
To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM).
Patients & Methods:
Patients (2010-2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A1c assessed during year postdiagnosis.
Results:
We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53-64%) for DM and 67% (95% CI: 64-71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02-1.79). Cancer did not harm glycemic control.
Conclusion:
OS among cancer patients with DM was lower than without DM.
Related Concept Videos
Psychoneuroimmunology: Diabetes and Cancer
Statistical Methods for Analyzing Epidemiological Data
Cancer Survival Analysis
Actuarial Approach
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

