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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

721
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

640
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
640
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

543
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

678
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

517
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Related Experiment Video

Updated: Nov 26, 2025

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

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Short Bowel Syndrome.

Baddr A Shakhsheer1, Brad W Warner1

  • 1Division of Pediatric Surgery, Saint Louis Children's Hospital, Department of Surgery, Washington University School of Medicine, Saint Louis, MO.

Current Treatment Options in Pediatrics
|December 14, 2020
PubMed
Summary
This summary is machine-generated.

Short gut syndrome (SBS) management has advanced through understanding intestinal adaptation and implementing multidisciplinary care. Focus on bowel preservation and complication mitigation improves outcomes and promotes enteral autonomy.

Keywords:
IFALDShort bowel syndromeintestinal adaptationintestinal failureparenteral nutrition

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Area of Science:

  • Gastroenterology
  • Surgical Outcomes
  • Intestinal Physiology

Background:

  • Short gut syndrome (SBS) is a severe condition often resulting from extensive small bowel resection.
  • Advances in understanding SBS pathophysiology have led to improved patient care and outcomes.

Purpose of the Study:

  • To review recent advancements in the care and management of patients with short gut syndrome.
  • To highlight strategies for promoting enteral autonomy and mitigating complications in SBS.

Main Methods:

  • Review of current literature on SBS management.
  • Analysis of physiological adaptations in remnant bowel.
  • Discussion of multidisciplinary approaches to intestinal rehabilitation.

Main Results:

  • Early care emphasizes bowel preservation and assessment of remnant bowel length/quality.
  • Intestinal adaptation involves bowel dilation, elongation, villus lengthening, crypt deepening, and gene expression changes.
  • Management strategies aim to augment adaptation and achieve enteral autonomy, with complication mitigation being crucial.

Conclusions:

  • Multidisciplinary teams are vital for improving outcomes in SBS through intestinal rehabilitation.
  • Practitioners require updated knowledge to promote enteral autonomy, recognize complications, and counsel patients effectively.