Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microskin grafting. I. Animal experiments.

M L Zhang1, Z D Chang, X Han

  • 1Department of Burns, Beijing Jishuitan Hospital, China.

Burns, Including Thermal Injury
|December 1, 1986
PubMed
Summary

Microskin grafting, a novel technique, effectively repairs extensive wounds using small autografts on homografts. This method shows promising results in wound healing with significant graft expansion ratios.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Analysis of clinical diagnosis, treatment, and pathogenic variants of hypoparathyroidism- sensorineural deafness-renal dysplasia (HDR) syndrome].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2026
Same author

[The mechanism of mitochondrial damage in chronic obstructive pulmonary disease induced by cigarette smoke and its therapeutic implications].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2025
Same author

[Correlation between complement deposition levels on blood cells and clinical biomarkers in patients with paroxysmal nocturnal hemoglobinuria].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

Growth of particles in a ternary melt.

The Journal of chemical physics·2025
Same author

[Association between sleep duration and blood pressure in school-age children: a cohort study].

Zhonghua yi xue za zhi·2025
Same author

[Kabuki syndrome caused by pathogenic variants in the <i>KMT2D</i> gene: report of two cases].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2025

Area of Science:

  • Regenerative Medicine
  • Wound Healing
  • Surgical Innovation

Background:

  • Extensive wounds pose significant challenges in treatment.
  • Autografts are limited by donor site availability.
  • Homografts can serve as a scaffold for autograft expansion.

Purpose of the Study:

  • To introduce and evaluate a novel microskin grafting technique.
  • To assess the efficacy of combining minced autografts with homografts for wound repair.
  • To determine the expansion ratios and healing times associated with this technique.

Main Methods:

  • Microskin grafting involved mincing autograft tissue into small pieces.
  • These pieces were spread onto a homograft, forming a combined graft.
  • The combined graft was transplanted onto experimental wounds in rabbits.

Main Results:

  • Microskin grafts were successful in 8 out of 12 rabbits.
  • Graft expansion ratios ranged from 7:1 to 15:1.
  • Wound healing occurred within 19 to 35 days, with successful graft take and orientation.

Conclusions:

  • Microskin grafting is an effective procedure for repairing extensive wounds.
  • The technique allows for significant wound coverage using minimal donor tissue.
  • Further research may optimize homograft integration to prevent displacement.

Related Experiment Videos