Heart failure after myocardial infarction: incidence and predictors

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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

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Dominik Jenča1,2, Vojtěch Melenovský1, Josef Stehlik3

  • 1Department of Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

ESC Heart Failure
|December 15, 2020
PubMed

Insights

Heart failure is a common complication after myocardial infarction. Identifying patients at risk early using multiple methods and starting treatment promptly can reduce the heart failure burden.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Heart failure (HF) frequently complicates myocardial infarction (MI).
  • Understanding epidemiology and risk factors for post-MI HF is crucial for patient outcomes.

Purpose of the Study:

  • To present an updated overview of the epidemiology and risk factors associated with heart failure development following myocardial infarction.
  • To identify predictive biomarkers for post-MI heart failure.

Main Methods:

  • Comprehensive literature review.
  • Identification of clinical, biochemical, genetic, and imaging risk factors and biomarkers.

Main Results:

  • Several clinical risk factors were identified.
  • Biochemical, genetic, and imaging biomarkers can predict HF development post-MI.

Conclusions:

  • Heart failure remains a frequent complication after myocardial infarction.
  • A multimodality approach to identify at-risk individuals is essential.
  • Early initiation of guideline-directed therapy can mitigate the HF burden.
Abstract

Keywords:
Adverse remodellingBiomarkersClinical risk factorsGeneticsHeart failure

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